Clindamycin
Clindamycin Information

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Clindamycin

medicine,pricing, side effects of Clindamycin medicine by company and complete information of medicines in pakistan here on this page including all packings, MG, dosage information. This list includes medicines and drugs over every region of Pakistan like Karachi, Lahore, Islamabad, Faisalabad, Rawalpindi, Multan, Peshawar, Quetta and other cities of Pakistan.

About Clindamycin

Clindamycin is an antibiotic. Chemically it is identified as 7-deoxy, 7-chloro derivative of of Lincomycin, an antobiotic that is elaborated by Streptomyces lincolnensis. It is effective against gram positive organism and many anaerobic bacteria. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the medication at regular interval of time throughout the day and night as prescribed. It is important to take the drug for the full time period as prescribed. If you discontinue the therapy, it may result in ineffective treatment. Clindamycin phosphate is used for the treatment of bacterial vaginosis.

Indications

Clindamycin is primarily indicated in conditions like Acne vulgaris, Babesiosis, Bacterial infections, Bacterial vaginosis, Dental infections, Endocarditis, Hidradenitis suppurativa, Intra-abdominal infections, Malaria, Osteomyelitis, Pelvic infections, Peritonitis, Pulmonary infection, Septic arthritis, Septicaemia, Soft tissue infections, Staphylococcal bone and joint infections, Systemic sepsis, Toxoplasmosis.

Contraindication

Clindamycin is contraindicated in conditions like Pseudomembranous colitis,Hypersensitivity.

Side Effects

The severe or irreversible adverse effects of Clindamycin, which give rise to further complications include Elevated SGPT & SGOT, Elevated alkaline phosphatase concentration, Esophageal ulceration, Severe diarrhea.Clindamycin produces potentially life-threatening effects which include Ventricular fibrillation, Anaphylactic shock, Pseudomembranous colitis, Cardiac Arrest, Colonic ulceration, Mucosal edema. which are responsible for the discontinuation of Clindamycin therapy.The symptomatic adverse reactions produced by Clindamycin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Nausea, Vomiting, Abdominal pain, Rashes, Vaginitis, Contact dermatitis, Leukocytoclastic angiitis, Local irritation, Reaction at injection site, Xerosis, Cervicitis.

Warnings

Clindamycin should be used with caution in patients with kidney or liver impairments and gastrointestinal diseases. Take appropriate measures in case of secondary infections.

High Risk Groups

Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Dosage

Clindamycin Dosage for Adults

Dose 300 to 600 mg
Single Dose 450 (450)
Frequency 6 hourly
Route IM, IV
Note: Should not Exceed 4.8g/day
Dose 150 to 450 mg
Single Dose 300 (300)
Frequency 6 hourly
Route PO
Note: Should not Exceed 1.8g/day

Clindamycin Dosage for Paedriatic

Dose 8 to 16 mg/kg
Single Dose 12 (12)
Frequency 6 hourly
Route serious infection
Dose 16 to 20 mg/kg
Single Dose 18 (18)
Frequency 6 hourly
Route more serious infection

Brands


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