Chorionic Gonadotrophin
Chorionic Gonadotrophin Information

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Chorionic Gonadotrophin

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About Chorionic Gonadotrophin

Chorionic Gonadotrophin is a hormone produced in placenta. It stimulates the ovaries and the testes. Chorionic Gonadotrophin is used in males to stimulate testicular descent or testicular growth and development. In females, Chorionic Gonadotrophin is used in combination with other medication to induce ovulation.

Indications

Chorionic Gonadotrophin is primarily indicated in conditions like Cryptorchidism (undescended testes), Hypogonadotrophic hypogonadism, Idiopathic male infertility, Induction of ovarian follicle maturation.

Contraindication

Chorionic Gonadotrophin is contraindicated in conditions like Precocious puberty,Ovarian hyperstimulation syndrome (OHS),Edema.

Side Effects

The severe or irreversible adverse effects of Chorionic Gonadotrophin, which give rise to further complications include Precocious puberty.Chorionic Gonadotrophin produces potentially life-threatening effects which include Ovarian hyperstimulation syndrome (OHSS). which are responsible for the discontinuation of Chorionic Gonadotrophin therapy.The symptomatic adverse reactions produced by Chorionic Gonadotrophin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Tiredness, Headache, Restlessness, Depression, Edema, Gynecomastia, Mood changes, Reaction at injection site, Pain at injection site, Pain at injection site.

Warnings

Chorionic gonadotrophin should not be used during pregnancy. It should be used with caution in patients with history of heart disease, kidney disease, asthma, migraine headaches, seizure disorder, cancer or any allergy.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, Geriatrics, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Dosage

Chorionic Gonadotrophin Dosage for Adults

Dose 5000 to 10000 IU
Single Dose 7500 (7500)
Frequency As recommended.
Route IM
Note: According to patient"s response.

Chorionic Gonadotrophin Dosage for Neonatal

Dose
Single Dose
Frequency
Route
Note: Not recommended in this age group

Chorionic Gonadotrophin Dosage for Paedriatic

Dose 50 to 100 IU/kg
Single Dose 75 (75)
Frequency As recommended.
Route Intra Muscular
Note: Alternate days for several weeks, (for boys)

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