Chloramphenicol
Chloramphenicol Information

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Chloramphenicol

medicine,pricing, side effects of Chloramphenicol medicine by company and complete information of medicines in pakistan here on this page including all packings, MG, dosage information. This list includes medicines and drugs over every region of Pakistan like Karachi, Lahore, Islamabad, Faisalabad, Rawalpindi, Multan, Peshawar, Quetta and other cities of Pakistan.

About Chloramphenicol

Chloramphenicol was first isolated in 1947 from the cultures of Streptomyces venezuelae. Chloramphenicol was synthesized in 1949, becoming the first completely synthetic antibiotic of importance to be produced commercially. Chloramphenicol is a broad spectrum antibiotic. Chloramphenicol is a nitrobenzene derivative. Chloramphenicol is primarily bacteriostatic and may be bacteriocidal to some strains. Chloramphenicol is active against both aerobic and anaerobic gram positive and gram negative organisms, rickettsiae and certain spirochetes. Adminitered orally or applied topically. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the drug at regular interval of time throughout the day and night as prescribed. Chloramphenicol is important to take the drug for the full time period as prescribed. If you discontinue the drug Chloramphenicol may result in ineffective treatment.

Indications

Chloramphenicol is primarily indicated in conditions like Acromegaly, Acute epiglottitis, Anaerobic infections, Bacterial infections, Blepharitis, Brain abscesses, Brucellosis, Cellulitis, Corneal ulcers, Intraocular infections, Iron deficiency anaemia, Keratoconjuctivitis sicca, Life threatning infections, Meningitis, Peritonitis, Plague, Psittacosis, Q Fever, Septicaemia, Spotted fever, Tularemia, Typhoid, and can also be given in adjunctive therapy as an alternative drug of choice in Enteritis, Gangrene, Haemophilia, Influenza, Whipple's disease.

Contraindication

Chloramphenicol is contraindicated in conditions like Hypersensitivity.

Side Effects

The severe or irreversible adverse effects of Chloramphenicol, which give rise to further complications include Encephalopathy, Pseudomembranous colitis, Urticaria, Thrombocytopenia, Hepatitis, Aplastic anemia, Hemolytic anemia, Aplastic anemia, Hemolytic anemia, Ototoxicity, Peripheral neuropathy, Optic neuritis, Hemolytic reactions, Interstitial nephritis, Hemolytic anemia, Aplastic anemia, Hair growth depression, Physical growth depression.Chloramphenicol produces potentially life-threatening effects which include Bone marrow suppression, Grey baby syndrome, Anaphylaxis. which are responsible for the discontinuation of Chloramphenicol therapy.The signs and symptoms that are produced after the acute overdosage of Chloramphenicol include Grey baby syndrome.The symptomatic adverse reactions produced by Chloramphenicol are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Nausea, Vomiting, Diarrhea, Maculopapular rash, Stomatitis, Confusion, Pruritus, Depression, Glossitis, Delirium, Vision disturbances, Confusion, Transient stinging, Typhoid, Salmonella infection.

Warnings

Evaluate blood count after every 2 days during therapy of chloramphenicol. Avoid concurrent therapy with other drugs that may cause bone marrow depression. It should be used with caution in case of liver or kidney disease. Discontinue therapy if secondry infection occurs.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.

Dosage

Chloramphenicol Dosage for Adults

Dose 0.5 %w/v
Single Dose 0.5 (0.5)
Frequency 2 hourly
Route Ophthalmic
Dose 1 %w/w
Single Dose 1 (1)
Frequency 6 hourly
Route Ophthalmic
Note: Frequency may be increased to 8 times if needed.
Dose 5 to 10 %
Single Dose 7.5 (7.5)
Frequency 6 hourly
Route Otic
Note: 1-2 drops.
Dose 50 to 100 mg/kg
Single Dose 75 (75)
Frequency 6 hourly
Route PO,IV
Note: Maximum dose: 4 g/day.

Chloramphenicol Dosage for Neonatal

Dose 12.5 to 25 mg/kg
Single Dose 19 (18.75)
Frequency 6 hourly
Route Intravenous
Dose 12.5 to 25 mg/kg
Single Dose 19 (18.75)
Frequency 6 hourly
Route oral

Chloramphenicol Dosage for Paedriatic

Dose 12.5 to 25 mg/kg
Single Dose 19 (18.75)
Frequency 6 hourly
Route Intra Venous
Note: -
Dose 12.5 to 25 mg/kg
Single Dose 19 (18.75)
Frequency 6 hourly
Route Oral
Note: -

Brands

1- ANTIBIOPTAL - 0.5%w/v MG

2- BENTHAPHEN - 1%w/w MG

3- BIOMYCINE - 1%w/v MG

4- BIOSTAT - 0.5%w/v MG

5- CHLORAMPHENICAL - 0.5%w/v MG

6- CHLORAMPHENICAL - 0.5%w/v MG

7- CHLORAMPHENICAL - 125mg/5ml MG

8- CHLORAMPHENICOL - 125mg/5ml MG

9- CHLORAMPHENICOL - 1g MG

10- CHLORAMPHENICOL - 0 MG

11- CHLORAMPHENICOL - 125mg/5ml MG

12- CHLORAMPHENICOL - 1%w/v MG

13- CHLORAMPHENICOL - 125mg/5ml MG

14- CHLORAMPHENICOL - 0.5%w/v MG

15- CHLORAMPHENICOL - 1%w/v MG

16- CHLORAMPHENICOL - 1g MG

17- CHLORAMPHENICOL - 125mg/5ml MG

18- CHLORAMPHENICOL - 125mg/5ml MG

19- CHLORAMPHENICOL - 250mg MG

20- CHLORAMPHENICOL - 250mg MG

21- CHLORAMPHENICOL - 250mg MG

22- CHLORAMPHENICOL - 1%w/v MG

23- CHLORAMPHENICOL - 0.5%w/v MG

24- CHLORAMPHENICOL - 250mg MG

25- CHLORAMPHENICOL - 250mg MG

26- CHLORAMPHENICOL - 250mg MG

27- CHLORAMPHENICOL - 250mg MG

28- CHLORAMPHENICOL - 1%w/w MG

29- CHLORAMPHENICOL - 1g MG

30- CHLORAMPHENICOL - 125mg/5ml MG

31- CHLORAMPHENICOL - 0.5%w/v MG

32- CHLORAMPHENICOL - 1%w/v MG

33- CHLORAMPHENICOL - 125mg/5ml MG

34- CHLORAMPHENICOL - 1g MG

35- CHLORAMPHENICOL - 1%w/v MG

36- CHLORAMPHENICOL - 125mg/5ml MG

37- CHLORAMPHENICOL - 250mg MG

38- CHLORAMPHENICOL - 125mg/5ml MG

39- CHLORAMPHENICOL - 125mg/5ml MG

40- CHLORAX - 1%w/w MG

41- CHLORAX - 1%w/w MG

42- CHLORDEX - 500mg MG

43- CHLORMAX - 0.5%w/v MG

44- CHLORMIC - 0.5%w/v MG

45- CHLOROFEN - 125mg/5ml MG

46- CHLOROGEN - 250mg MG

47- CHLOROGEN - 250mg MG

48- CHLOROGEN - 125mg/5ml MG

49- CHLOROMAX - 1g MG

50- CHLOROMED - 1g MG

51- CHLOROMYCETIN - 250mg MG

52- CHLOROMYCETIN - 1%w/w MG

53- CHLOROMYCETIN - 1g MG

54- CHLOROMYCETIN FORTE - 500mg MG

55- CHLOROMYCETIN HC - 1%w/w MG

56- CHLOROMYCETIN PALMITATE - 125mg/5ml MG

57- CHLOROPHENICOL - 250mg MG

58- CHLOROPHENICOL - 0 MG

59- CHLOROPHENICOL - 1g MG

60- CHLOROPTIC - 0.5%w/v MG

61- CLORAMIDINA - 0.5%w/v MG

62- CLORAMIDINA - 0.5%w/w MG

63- CLORAMIDINA COMPLEX - 0 MG

64- CLORAMIDINA H - 1%w/w MG

65- CODOHYST - 2mg/5ml MG

66- COMYCETIN - 1%w/v MG

67- COMYCETIN - 0.5%w/v MG

68- DECACHLOR - 0.5%w/v MG

69- DEXACHLOR - 0.5%w/v MG

70- DEXACOR - 5mg MG

71- DEXOPTIC-C - 0.5%w/v MG

72- DILOCAL - 1%w/v MG

73- DOSACHLOR - 0.5%w/v MG

74- ECONOCHLOR - 0.5%w/v MG

75- ELKOPHENICOL S - 1g MG

76- EPOPHENICOL - 250mg MG

77- EPOPHENICOL - 250mg MG

78- EPOPHENICOL - 1%w/v MG

79- EPOPHENICOL - 0.5%w/v MG

80- EPOPHENICOL - 125mg/5ml MG

81- EPOPHENICOL - 125mg/5ml MG

82- EROPHENICOL - 0.5%w/v MG

83- EROPHENICOL - 0.5%w/v MG

84- EYCHLOR - 0.5%w/v MG

85- EYCHLOR - 0.5%w/v MG

86- FENICOL - 250mg MG

87- FENICOL - 250mg MG

88- FENOPTIC - 0.5%w/v MG

89- FLUOROBIOPTAL - 0.5%w/v MG

90- GEOCLOR - 1%w/w MG

91- INVOCLOR - 0.5%w/v MG

92- INVOCLOR - 1%w/w MG

93- IRZAPHENICOL - 125mg/5ml MG

94- IRZAPHENICOL - 125mg/5ml MG

95- KLORECAL - 0.5%w/v MG

96- KOHSCLOR - 125mg/5ml MG

97- KOHSCLOR - 125mg/5ml MG

98- LEVOCORT - 1%w/v MG

99- LEVOCORT - 1%w/w MG

100- LEXICOL - 0.5%w/v MG

101- LISKOMYCETIN - 125mg/5ml MG

102- LORAM - 125mg/5ml MG

103- M-PHENICOL - 125mg/5ml MG

104- M-PHENICOL - 125mg/5ml MG

105- MANOPHENICOL - 0.5%w/v MG

106- MANOPHENICOL - 1%w/v MG

107- MAVICHLOR - 250mg MG

108- MB-CHLOR - 1%w/v MG

109- MB-CHLOR - 0.5%w/v MG

110- MB-CHLOR - 125mg/5ml MG

111- MEDCLOR - 250mg MG

112- MEDICHLOR PLUS - 0.5%w/v MG

113- MEDIDEX-C - 0.5%w/v MG

114- MEDIKUF - 5mg/5ml MG

115- METHACHLOR - 1%w/v MG

116- METHACHLOR - 1%w/w MG

117- MONCOL - 25mg/5ml MG

118- MONOPHENICOL - 0.5%v/v MG

119- NEO-PHENICOL - 1%w/v MG

120- NEO-PHENICOL - 0.5%w/v MG

121- NEO-PHENICOL - 1%w/w MG

122- NEO-PHENICOL - 125mg/5ml MG

123- NEO-PHENICOL H.C. - 1%w/w MG

124- NEOBREX - 0.3%w/v MG

125- NEOBREX - 0.3%w/w MG

126- NOVOPHENICOL - 250mg MG

127- NOVOPHENICOL - 250mg MG

128- NOVOPHENICOL - 1%w/w MG

129- NOVOPHENICOL - 125mg/5ml MG

130- NOVOPHENICOL - 125mg/5ml MG

131- O-MYCETIN - 0.5%w/v MG

132- OCUCHLOR - 00 MG

133- OCUPRED FORTE - 0%w/v MG

134- OCUPRED-CHLOR - 0 MG

135- OMYCETIN - 1%w/v MG

136- OMYCETIN - 0.5%w/v MG

137- OMYCETIN - 1%w/w MG

138- OPCHLOR - 0.5%w/v MG

139- OPHTH-CHLOR - 0.5%w/v MG

140- OPTACHLOR - 0.5%w/v MG

141- OPTACHLOR - 1%w/w MG

142- ORBACHLOR - 0.5%w/v MG

143- ORICOL - 0.5%w/v MG

144- PHENICHLOR - 125mg/5ml MG

145- PHENICOL - 125mg/5ml MG

146- PHENICOL - 125mg/5ml MG

147- PLIPHENICOL - 0 MG

148- PREDNI-C - 0.2%w/v MG

149- PREDNICOL - 0.5%w/v MG

150- PREDNISYNTH - 0.5%w/v MG

151- PREDSIN - 0.2%w/v MG

152- REMICOL - 1%w/v MG

153- REXAPHENICOL - 0 MG

154- SANTOCHLOR - 0.5%w/v MG

155- SANTOCHLOR - 1%w/w MG

156- SCHAZOMYCETIN - 0.5%w/v MG

157- SEMOFENICOL - 250mg MG

158- SEMOFENICOL - 125mg/5ml MG

159- SIFICETINA - 0.5%w/v MG

160- SIFICETINA - 1%w/w MG

161- SPERSADEX COMPOUND - 0.5%w/v MG

162- SPERSADEXOLINE - 0.5%w/v MG

163- SPERSANICOL - 0.5%w/v MG

164- UNIPHENICOL - 125mg/5ml MG

165- VASOCHLOR - 0.5%w/v MG

166- VECHLOR - 0.5%w/v MG

167- VEGACHLOR - 0.5%w/v MG

168- VI-CHLOR - 0 MG

169- VITACHLOR - 0.5%w/v MG

170- XANTERVIT - 1%w/w MG

171- ZALOMYCETIN - 0 MG

172- ZALOMYCETIN - 0 MG


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