Calcifediol
Calcifediol Information

About Calcifediol

Calcifediol is a vitamin D3, a fat soluble sterol, sometimes considered to be hormone or hormone precursor. Calcifediol is involved in promoting normal bone development in body by regulating calcium, phosphorus and minerals. Vitamin D is a secosteroid and sometimes popularly known as the 'sunshine vitamin' because formed in the skin from 7-dehydrocholesterol under the influence of ultraviolet irradiation. Calcifediol is also found in certain foods. Fish liver oils especially code liver oil are good sources of vitamin D.Calcifediol is used topically as a teratment of psoriasis

Indications

Calcifediol is primarily indicated in conditions like Cholestasis, Hyperparathyroidism, Hypoparathyroidism, Malabsorption, Nephrotic syndrome, Nutritional osteomalacia, Renal failure, Short bowel syndrome, Vitamin D deficiency rickets, Vitamin D-resistant rickets.

Contraindication

Calcifediol is contraindicated in conditions like Hypercalcaemia,Granulomatous disease.

Side Effects

The severe or irreversible adverse effects of Calcifediol, which give rise to further complications include Urinary stone formation.Calcifediol produces potentially life-threatening effects which include Hypercalcemia, Hyperphosphatemia, Hypermagnesemia, Calcification in arteries & soft tissues. which are responsible for the discontinuation of Calcifediol therapy.The signs and symptoms that are produced after the acute overdosage of Calcifediol include Hypercalcemia.The symptomatic adverse reactions produced by Calcifediol are more or less tolerable and if they become severe, they can be treated symptomatically, these include Weakness, Thirst, Headache, Nausea, Vomiting, Anorexia, Abdominal pain, Apathy, Somnoparalytic ileus, Cardiac arrhythmias, Polyuria, Dehydration.

Warnings

Evaluate Vitamin D administration in fortified food, diet and drugs. It may be necessary to limit dietary Vit.D during treatment. If products of Vitamin D contain tartrazine may cause allergic reaction (including bronchial asthma) in susceptible individuals, especially patients with aspirin hypersensitivity.

High Risk Groups

Drug should not be given to patients suffering from Kidney dysfunction.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.