Buprenorphine (HCl)
Buprenorphine (HCl) Information

About Buprenorphine (HCl)

Buprenorphine (HCl) is a synthetic derivative of thebaine. Buprenorphine (HCl) is narcotic analgesic. Buprenorphine (HCl) is used to relieve the moderate to severe pain and as an adjunct to anesthesia.

Indications

Buprenorphine (HCl) is primarily indicated in conditions like Adjunct in the treatment of opiod dependence, Adjunct to prevent relapse, Advanced breast cancer in postmenopausal women, All forms of epilepsy, Cocaine withdrawal, Moderate to severe acute pain, Moderate to severe chronic pain, Moderate to severe pain, Myoclonus, Opioid agonist dependence, Post operative analgesia.

Contraindication

Buprenorphine (HCl) is contraindicated in conditions like Phaeochromocytoma,Respiratory disease,Paralytic ileus,Head injury,Atrophic oral candidiasis associated with dentures.

Side Effects

The severe or irreversible adverse effects of Buprenorphine (HCl), which give rise to further complications include Hallucinations.Buprenorphine (HCl) produces potentially life-threatening effects which include Respiratory depression. which are responsible for the discontinuation of Buprenorphine (HCl) therapy.The symptomatic adverse reactions produced by Buprenorphine (HCl) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Vertigo, Headache, Nausea, Vomiting, Constipation, Sweating.

Warnings

Buprenorphine should be used with caution and in low doses in patients with lungs, liver or kidney impairment, central nervous system (CNS) depression or patients undergoing biliary tract surgery. Patients should observe caution while driving or performing tasks requiring alertness, because it may cause drowsiness.

High Risk Groups

Drug should not be given to Pregnant Mothers, patients suffering from Liver Malfunction, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.