Bromocriptine (Mesylate)
Bromocriptine (Mesylate) Information

About Bromocriptine (Mesylate)

Bromocriptine (Mesylate) is the 2-bromo derivative of a-ergocryptine. Bromocriptine an ergotamine (an alkaloid with vasoconstrictor action), is a dopamine agonist and mimics the action of dopamine. The effects of bromocriptine are similar to those fo Levodopa. The drug produces little effects in patients who do not react to Levodopa. But Bromocriptine (Mesylate) is often used with Levodopa in patients responding to drug therapy.

Indications

Bromocriptine (Mesylate) is primarily indicated in conditions like Acromegaly, Anovulatory infertility, Cyclical benign breast disease, Galactorrhoea, Hyperprolactinaemia, Hypogonadism, Infertility, Infertility without hyperprolactinaemia, Parkinsonism, Parkinson's disease, Premenstrual syndrome, Premenstural syndrome, Prolactinoma, Suppression of lactation, and can also be given in adjunctive therapy as an alternative drug of choice in Lactation.

Contraindication

Bromocriptine (Mesylate) is contraindicated in conditions like Hypertension in pregnancy,Toxaemia of pregnancy,Neurological disorders,Breast disease,Hypersensitivity to the drug.

Side Effects

The severe or irreversible adverse effects of Bromocriptine (Mesylate), which give rise to further complications include Pleural effusion, Parkinsonism.The signs and symptoms that are produced after the acute overdosage of Bromocriptine (Mesylate) include Nausea, Vomiting, Drowsiness, Hallucinations, Postural hypotension, Dizziness, Sweating.The symptomatic adverse reactions produced by Bromocriptine (Mesylate) are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Fatigue, Nausea, Vomiting, Confusion, Hallucination, Postural hypotension.

Warnings

Bromocriptine should be used with caution in patients with history of heart attack, angina (heart pain), liver disease, kidney disease, psychiatric illness or circulation problems in the fingers in cold weather. This medication should be used only when clearly needed during pregnancy. This drug is not recommended during lactation.

High Risk Groups

Drug should not be given to Paediatrics, Pregnant Mothers, and Neonates.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.