Adefovir Dipivoxil
Adefovir Dipivoxil Information

About Adefovir Dipivoxil

Chlorquinaldol, 5,7-dichloro-2-methyl-8-hydroxyquinoline, has antibacterial, antifungal and amoebicidal activity with antieczematic and antipruritic properties; used topically in the treatment of cutaneous and vaginal infections. It is a similar agent to clioquinol.

Indications

Adefovir Dipivoxil is primarily indicated in conditions like Viral hepatitis.

Contraindication

Adefovir Dipivoxil is contraindicated in conditions like Hypersensitivity,Breast feeding.

Side Effects

The severe or irreversible adverse effects of Adefovir Dipivoxil, which give rise to further complications include Renal failure.The symptomatic adverse reactions produced by Adefovir Dipivoxil are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Diarrhea, Abdominal pain, Dyspepsia, Asthenia, Nausea and vomiting, Hypophosphatemia, dyspepsia.

Warnings

Patients should be monitored closely for adverse events when Adefovir dipivoxil is co-administered with drugs that are excreted renally or with other drugs known to affect renal function. Hepatic function should be monitored at repeated intervals with both clinical and laboratory follow-up for at least several months in patients who discontinue Adefovir dipivoxil. It is important to monitor renal function for all patients during treatment. Caution should be exercised when prescribing Adefovir dipivoxil to adolescents with underlying renal dysfunction, and renal function in these patients should be closely monitored. Particular caution should be exercised when administering nucleoside analogs to any patient with known risk factors for liver disease. Obtaining HIV antibody testing prior to starting Adefovir dipivoxil is important.

High Risk Groups

Drug should not be given to Pregnant Mothers, patients suffering from Kidney dysfunction, patients suffering from Liver Malfunction, and Geriatrics.If prescribing authority justifies the benefits of the drug against the possible damages he/she should reevaluate them and consult the reference material and previous studies.